Alzheimer's disease assays

Returns a tibble containing curated metadata for assay implementations used to measure fluid or imaging biomarkers relevant to Alzheimer's disease research. Each row describes a specific combination of vendor, platform, and technology used to quantify a given analyte.

Assays represent product-specific implementations (e.g., Elecsys, Simoa HD-X, INNOTEST) that produce numeric measurements for downstream biomarker classification. Quantitative performance parameters such as lower and upper limits of quantification (LLOQ, ULOQ) are included where available.

Usage

assays()

Value

A tibble with the following columns:

assay_id

Unique identifier for the assay.

analyte_id

Reference to the measured analyte (see analytes()).

modality

Either "fluid" or "imaging", denoting the type of measurement.

matrix

Biological specimen used, such as "CSF", "plasma", or "brain".

cv

Coefficient of variation.

lloq

Lower limit of quantification.

uloq

Upper limit of quantification.

unit

Measurement unit (e.g., "pg/mL", "SUVR").

technology

Underlying method used (e.g., "ELISA", "PET", "Simoa").

vendor

Manufacturer of the assay.

platform

Commercial platform or product line name.

description

Descriptive label for the assay.

See also

analytes(), biomarkers()

Examples

assays()
#> # A tibble: 22 × 12
#>    assay_id analyte_id modality matrix cv     lloq  uloq unit  technology vendor
#>    <chr>    <chr>      <chr>    <chr>  <lgl> <dbl> <dbl> <chr> <chr>      <chr> 
#>  1 innotes… CHEBI:646… fluid    CSF    NA    225    1452 pg/mL ELISA      Fujir…
#>  2 innotes… CHEBI:646… fluid    CSF    NA      3.4 10000 pg/mL ELISA      Fujir…
#>  3 lumipul… CHEBI:646… fluid    CSF    NA     NA      NA pg/mL CLEIA      Fujir…
#>  4 lumipul… CHEBI:646… fluid    CSF    NA     NA      NA pg/mL CLEIA      Fujir…
#>  5 euroimm… CHEBI:646… fluid    CSF    NA     NA      NA pg/mL ELISA      EUROI…
#>  6 euroimm… CHEBI:646… fluid    CSF    NA     NA      NA pg/mL ELISA      EUROI…
#>  7 innogen… CHEBI:646… fluid    CSF    NA     NA      NA pg/mL ELISA      Innog…
#>  8 innogen… CHEBI:646… fluid    CSF    NA     NA      NA pg/mL ELISA      Innog…
#>  9 msd-ab4… CHEBI:646… fluid    CSF    NA     NA      NA pg/mL ECLIA      MSD   
#> 10 msd-ab4… CHEBI:646… fluid    CSF    NA     NA      NA pg/mL ECLIA      MSD   
#> # ℹ 12 more rows
#> # ℹ 2 more variables: platform <chr>, description <chr>